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Early signs can only be seen with a PET scan. Metastisis is usually to the pelvic and lower back bones but also can attack various organs including the bladder, liver, kidneys, lungs, and brain. I'm not a medical professional but, since I'm a patient, I've done a ton of research on this subject. I now have a recurrence so this is what I will be looking at down the road. With a recurrence there is a 50/50 chance that it has already spread.