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I've been on 75/mg of sertraline (generic version of Zoloft) for 5 years. It has helped a great deal with my depression, anxiety, and compulsive negative thoughts. I've gotten off of it twice; I find that I don't have withdrawal symptoms if I go off it gradually. The side effects I've had are a decrease in sex drive (which comes back once I stop taking it) and a general feeling of apathy. It doesn't make me happy, it just makes me not so sad and much less obsessive. I do, however, feel I have lost a lot of creativity and motivation. Other than the apathy and lack of a sex drive, it works extremely well at stopping the depression and anxiety.

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