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I have been put on Synthroid about three months ago to treat my underactive thyroid. Before I tried Synthroid I had tried out several other meds but they were either not sufficiently effective for me or caused side effects I couldn't tolerate. In general I almost got used to feeling constant exhaustion, cold intolerance, and extreme tiredness. My skin was so horribly dry and I couldn't change this condition in any way. I used to buy tons of nourishing and moisturizing creams and rubbed it all over my body to get rid of those nasty sensations of itching, cracking and irritation. Besides I had severe problems with water retention. I needed to strictly control water intake in order to keep myself conscious. With Synthroid many of those problems disappeared completely. I feel so much better now that I can not actually believe it. Now I am working at the extra weight I have gained when concentrated on my search for a medication that would drive away the worst symptoms. I am sure with Synthroid I'll achieve good results and will bring the quality of my life to a much higher level.