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I really don't know how to rate this medication. I only took it for about 3 weeks at 50mg per day. It really helped with depression and with anxiety. I have both depression & panic disorder. But, I started getting what I thought was acne everywhere. Now, I think it is some sort of allergic reaction because it is getting worse and I am very itchy & my skin feels hot to touch. I'm not sure. So I stopped taking it 6 days ago. I am extremely depressed now and the hives are getting worse each day and I am exhausted. I can hardly get up in the mornings. But the hives are just awful. I keep waiting for them to go away now. I am so itchy and very tired. The red bumps are all over my face, neck, and torso.