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insomnia and severe dry mouth, I made sure to carry gum. I have been on the medicines twice one year apart, lost 22 lbs the last round and it was such a great feeling. It ended all cravings, even for chocolate! Unfortunately as soon as I stopped the medicines after 6 months, I gained it all back. I ended up with heart problems, not sure if the Meridia was to blame, (I have a history of cardiac issues). I am to blame, I stopped exercising and all my cravings came back. I loved the results so much, I want another shot despite side effects.